rLG3 Restores the BBB and Improves Function
Dramatic Effects in Multiple Preclinical Models & Studies
- Improves Function & Saves Brain following impact traumatic brain injury (TBI)
- Highly efficacious with a single dose
- Reduces cell death (NSE quantification)
- Rapidly improves functional performance
- Beam walk/coordination
- 4-limb grip strength
- Improves BBB integrity in impact region
- Improves function in repeat mild blast injury (data not shown)
Restores BBB 24 hours After Severe TBI
TBI - Control vs TBI - LG3 Comparison
Improved Functional Outcomes
Beam Walk & Grip Strength
Significant Neuroprotection
Neuronal Injury Imaging
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